A recent book about Agricola's conquest of Scotland presents a Scottish historian's take on a subject that has been dominated by archaeologists: the whereabouts of Mons Graupius, the scene of Agricola's final battle. Unfortunately, in confidently locating it in Perthshire, author James Fraser builds his case on shaky foundations.

Background Several jurisdictions, including Singapore, Australia, New Zealand and most recently Ireland, have a public interest or public good criterion for granting waivers of consent in biomedical research using secondary health data or tissue. However, the concept of the public interest is not well defined in this context, which creates difficulties for institutions, institutional review boards and regulators trying to implement the criterion. Main text This paper clarifies how the public interest criterion can be defensibly deployed. We first explain the (...) ethical basis for requiring waivers to only be granted to studies meeting the public interest criterion, then explore how further criteria may be set to determine the extent to which a given study can legitimately claim to be in the public interest. We propose an approach that does not attempt to measure magnitude of benefit directly, but rather takes into account metrics that are more straightforward to apply. To ensure consistent and justifiable interpretation, research institutions and IRBs should also incorporate procedural features such as transparency and public engagement in determining which studies satisfy the public interest requirement. Conclusion The requirement of public interest for consent waivers in secondary biomedical research should be guided by well-defined criteria for systematic evaluation. Such a criteria and its application need to be periodically subject to intra-committee and intra-institution review, reflection, deliberation and amendment. (shrink)

First published in 1973, this was the first detailed comparative analysis of the writings of Karl Marx and John Stuart Mill. it contains a full, careful and sympathetic account of their respective social doctrines, and concludes with a critical comparative evaluation of the two thinkers.

Marx did not approach the state in answer to some such broad and abstract philosophical question as: What is the state? Nor did he offer a full sociological or historical or analytic account of state institutions and functions, and there are hence clear and substantial dangers in extrapolating to all or most conditions an account which is, in large part, specific to bourgeois society. Failing a comprehensive and formal treatise on politics and the state, Marx's own discussion consists of a (...) number of scattered and not altogether consistent general observations and some detailed investigation of the role and character of the state in particular historical situations. It seems sensible, then, to begin an elucidation of his account of the state with a comment on the nature of his interest in the subject. Why did he need a theory of the state? At what points does it become important to his explanatory and his revolutionary doctrines? (shrink)

Marx did not approach the state in answer to some such broad and abstract philosophical question as: What is the state? Nor did he offer a full sociological or historical or analytic account of state institutions and functions, and there are hence clear and substantial dangers in extrapolating to all or most conditions an account which is, in large part, specific to bourgeois society. Failing a comprehensive and formal treatise on politics and the state, Marx's own discussion consists of a (...) number of scattered and not altogether consistent general observations and some detailed investigation of the role and character of the state in particular historical situations. It seems sensible, then, to begin an elucidation of his account of the state with a comment on the nature of his interest in the subject. Why did he need a theory of the state? At what points does it become important to his explanatory and his revolutionary doctrines? (shrink)

The human major histocompatibility complex (MHC), on the short arm of chromosome 6, represents one of the most extensively characterised regions of the human genome. This ∼4 Mb segment of DNA contains genes encoding the polymorphic MHC class I and class II molecules which are involved in antigen presentation during an immune response. Recently the whole of the MHC has been cloned in cosmids and/or yeast artificial chromosomes (YACs) and large portions have been characterised for the presence of novel genes. (...) Many unrelated genes, both housekeeping and tissue specific, have been identified and the gene density in some regions is now approaching one gene every few kilobases. Some of the novel genes encode proteins involved in the intracellular processing and transport of antigens that are presented by MHC class I molecules. Others, however, have no obvious role in the immune response. The MHC is located in the chromosome band 6p21.3 which is a Giemsa (G)‐light band. The detection of such a large number of functional genes (at least 70) in this region is compatible with the idea that both housekeeping and tissue‐specific genes are localised predominantly in G‐light bands. (shrink)

There are two main questions in epistemology: What is knowledge? And: Do we have any of it? The first question asks after the nature of a concept; the second involves grappling with the skeptic, who believes that no one knows anything. This collection of original essays addresses the themes of knowledge and skepticism, offering both contemporary epistemological analysis and historical perspectives from leading philosophers and rising scholars. Contributors first consider knowledge: the intrinsic nature of knowledge -- in particular, aspects of (...) what distinguishes knowledge from true belief; the extrinsic examination of knowledge, focusing on contextualist accounts; and types of knowledge, specifically perceptual, introspective, and rational knowledge. The final chapters offer various perspectives on skepticism. Knowledge and Skepticism provides an eclectic yet coherent set of essays by distinguished scholars and important new voices. The cutting-edge nature of its contributions and its interdisciplinary character make it a valuable resource for a wide audience -- for philosophers of language as well as for epistemologists, and for psychologists, decision theorists, historians, and students at both the advanced undergraduate and graduate levels. Contributors: Kent Bach, Joseph Keim Campbell, Joseph Cruz, Fred Dretske, Catherine Z. Elgin, Peter S. Fosl, Peter J. Graham, David Hemp, Michael O'Rourke, George Pappas, John L. Pollock, Duncan Pritchard, Joseph Salerno, Robert J. Stainton, Harry S. Silverstein, Joseph Thomas Tolliver, Leora Weitzman The hardcover edition does not include a dust jacket. (shrink)

David Gauthier thinks agents facing a prisoner's dilemma ('pd') should find it rational to dispose themselves to co-operate with those inclined to reciprocate (i.e., to acquire a constrained maximizer--'cm'--disposition), and to co-operate with other 'cmers'. Richmond Campbell argues that since dominance reasoning shows it remains to the agent's advantage to defect, his co-operation is only rational if cm "determines" him to co-operate, forcing him not to cheat. I argue that if cm "forces" the agent to co-operate, he is not (...) acting at all, never mind rationally. Thus, neither author has shown that co-operation is rational action in a pd. (shrink)

New essays by leading philosophers explore topics in epistemology, offering both contemporary philosophical analysis and historical perspectives. There are two main questions in epistemology: What is knowledge? And: Do we have any of it? The first question asks after the nature of a concept; the second involves grappling with the skeptic, who believes that no one knows anything. This collection of original essays addresses the themes of knowledge and skepticism, offering both contemporary epistemological analysis and historical perspectives from leading philosophers (...) and rising scholars. Contributors first consider knowledge: the intrinsic nature of knowledge—in particular, aspects of what distinguishes knowledge from true belief; the extrinsic examination of knowledge, focusing on contextualist accounts; and types of knowledge, specifically perceptual, introspective, and rational knowledge. The final chapters offer various perspectives on skepticism. Knowledge and Skepticism provides an eclectic yet coherent set of essays by distinguished scholars and important new voices. The cutting-edge nature of its contributions and its interdisciplinary character make it a valuable resource for a wide audience—for philosophers of language as well as for epistemologists, and for psychologists, decision theorists, historians, and students at both the advanced undergraduate and graduate levels. Contributors Kent Bach, Joseph Keim Campbell, Joseph Cruz, Fred Dretske, Catherine Z. Elgin, Peter S. Fosl, Peter J. Graham, David Hemp, Michael O'Rourke, George Pappas, John L. Pollock, Duncan Pritchard, Joseph Salerno, Robert J. Stainton, Harry S. Silverstein, Joseph Thomas Tolliver, Leora Weitzman. (shrink)

An epistemological how-possible question asks how knowledge, or knowledge of some specific kind, is possible. The main contention of Duncan Pritchard‟s stimulating comments is that what I call „explanatory minimalism‟ appears to offer us just what we are seeking when we ask such a question. This looks like a problem for me given that I defend a version of explanatory anti-minimalism. Pritchard outlines a version of minimalism inspired by the writings of John McDowell and does not find it obvious (...) that this position is lacking in any relevant respect. Nor do I. My minimalism is moderate rather than extreme but Pritchard‟s objections to anti-minimalism are objections to extreme anti-minimalism. Indeed, his comments do not seem to me to have any direct bearing on what I take to be the fundamental disagreement between minimalism and anti-minimalism. (shrink)

An experimenting society is one in which policy-relevant knowledge is created. It is then critically assessed and communicated in real-life or natural settings, with the aim of discovering new forms of public action to improve the problem-solving capacities of society. This latest volume of the distinguished Policy Studies Review Annual series probes, evaluates, and augments the work of Donald T. Campbell on an experimental societies. A basic assumption of this volume is that Campbell's perspective supplies a useful way (...) to address increasingly complex and seemingly unmanageable problems facing the United States and other postindustrial societies. This volume is also the fourteenth festschrift to be issued by Transaction. The focus is on theoretical as well as practical options for creating an experimenting society. The rationale for this focus is the belief, increasingly -shared in the social science and policy-making communities alike, that researchers are essentially ignorant about how to solve many of the most pressing larger problems of this epoch. This frank recognition of ignorance is a prerequisite of genuine scientific and professional curiosity, without which knowledge gains are next to impossible to achieve, and a'precondition of an experimenting society. Contributors to this original volume include: Steve-Fuller, Duncan MacRae, Jr., Anthony S. Bryk, Robert A. Beauregard, Rita Mae Kelly, Peter Gregware, Burkart Holzner, B. Guy Peters, C. West Churchman, and Ian I. Mitroff. Their multidisciplinary competencies are at once philosophical, methodological, and substantive. They address such questions as: What new or bold policies are available in domains such as education, science, and urban development? In what ways can theoretical knowledge and practical action be fused so as to illuminate or alleviate policy problems? What should be done? Included are excerpts from Campbell's foundational paper "The Experimenting Society," as well as a recent article entitled "Methods for the Experimenting Society," which circulated in unpublished form for many years. An unusual feature of the book is Campbell's responses to those who have addressed his work with candor and intelligence. It will be of interest to policy studies scholars, sociologists, and social scientists. (shrink)

This book traces how such a seemingly immutable idea as measurement proved so malleable when it collided with the subject matter of psychology. It locates philosophical and social influences reshaping the concept and, at the core of this reshaping, identifies a fundamental problem: the issue of whether psychological attributes really are quantitative. It argues that the idea of measurement now endorsed within psychology actually subverts attempts to establish a genuinely quantitative science and it urges a new direction. It relates views (...) on measurement by thinkers such as Holder, Russell, Campbell and Nagel to earlier views, like those of Euclid and Oresme. Within the history of psychology, it considers contributions by Fechner, Cattell, Thorndike, Stevens and Suppes, among others. It also contains a non-technical exposition of conjoint measurement theory and recent foundational work by leading measurement theorist R. Duncan Luce. (shrink)

Preface Introduction Christopher J. Berry: Adam Smith: Outline of Life, Times, and Legacy Part One: Adam Smith: Heritage and Contemporaries 1: Nicholas Phillipson: Adam Smith: A Biographer's Reflections 2: Leonidas Montes: Newtonianism and Adam Smith 3: Dennis C. Rasmussen: Adam Smith and Rousseau: Enlightenment and counter-Enlightenment 4: Christopher J. Berry: Adam Smith and Early Modern Thought Part Two: Adam Smith on Language, Art and Culture 5: Catherine Labio: Adam Smith's Aesthetics 6: James Chandler: Adam Smith as Critic 7: Michael C. (...) Amrozowicz: Adam Smith: History and Poetics 8: C. Jan Swearingen: Adam Smith on Language and Rhetoric: The Ethics of Style, Character, and Propriety Part Three: Adam Smith and Moral Philosophy 9: Christel Fricke: Adam Smith: The Sympathetic Process and the Origin and Function of Conscience 10: Duncan Kelly: Adam Smith and the Limits of Sympathy 11: Ryan Patrick Hanley: Adam Smith and Virtue 12: Eugene Heath: Adam Smith and Self-Interest Part Four: Adam Smith and Economics 13: Tony Aspromourgos: Adam Smith on Labour and Capital 14: Nerio Naldi: Adam Smith on Value and Prices 15: Hugh Rockoff: Adam Smith on Money, Banking, and the Price Level 16: Maria Pia Paganelli: Commercial Relations: from Adam Smith to Field Experiments Part Five: Adam Smith on History and Politics 17: Spiros Tegos: Adam Smith: Theorist of Corruption 18: David M. Levy & Sandra J. Peart: Adam Smith and the State: Language and Reform 19: Fabrizio Simon: Adam Smith and the Law 20: Edwin van de Haar: Adam Smith on Empire and International Relations Part Six: Adam Smith on Social Relations 21: Richard Boyd: Adam Smith, Civility, and Civil Society 22: Gavin Kennedy: Adam Smith on Religion 23: Samuel Fleischacker: Adam Smith and Equality 24: Maureen Harkin: Adam Smith and Women Part Seven; Adam Smith: Legacy and Influence 25: Spencer J. Pack: Adam Smith and Marx 26: Craig Smith: Adam Smith and the New Right 27: Tom Campbell: Adam Smith: Methods, Morals and Markets 28: Amartya Sen: The Contemporary Relevance of Adam Smith. (shrink)

Mill’s socialism and democratic theory have led some scholars to accuse him of trying to eliminate conflict from political life. Whereas Graeme Duncan has averred that Mill’s socialism aims to institute a completely harmonious society, James Fitzjames Stephen has contended that Millian democracy sought to evacuate conflict from political discussion. This article reconstructs both critiques and argues they are imprecise. Even if disputes motivated by redistribution of material goods would no longer exist in an egalitarian society, conflicts driven (...) by resentment over social reputation would keep the flame of conflict burning in a Millian socialist community. Moreover, a close reading of Considerations on Representative Government shows that Mill knew that no amount of political discussion is able to make conflicting opinions disappear. According to him, conflict is unavoidable in democratic politics because citizens analyse political issues from different social perspectives. Mill’s goal was not to eliminate conflict, but rather to regulate it in such a way as to bring about its attendant benefits, namely, progress and self-development. (shrink)

The Growing-Block view of time has some problems with the past. It is committed to the existence of the past, but needs to say something about the difference between the past and present. I argue that we should resist Correia and Rosenkranz’ response to Braddon-Mitchell’s argument that the Growing-Block leads to scepticism about whether we are present. I consider an approach, similar to Peter Forrest, and show it is not so counter-intuitive as Braddon-Mitchell suggests and further show that it requires (...) no ‘semantic and metaphysical gymnastics’, as Chris Heathwood has suggested. In doing these things I make the problem of the past on the Growing-Block view a problem in its history, not its present. (shrink)

The conversation with Jill H. Casid and Anna Campbell is a reconceptualization of several themes to develop an aesthetic that incorporates notions of the necropolitical and redefines the concept of the Anthropocene as the Necrocene. The Necrocene implies an era marked by death, decay, and the consequences of human impact on the environment, as well as a critical reflection on the choices individuals and societies make that contribute to the transition from the Anthropocene to the Necrocene. These reflections serve (...) as cautionary tales or reflections on the unsustainable path of the Anthropocene. An important reflection in the interview is how queer and transgender people are using art and assemblages to refuse the terms of the current tensions of the culture wars. (shrink)

Filling the need for an accessible, carefully structured introductory text in symbolic logic, Modern Logic has many features designed to improve students' comprehension of the subject, including a proof system that is the same as the award-winning computer program MacLogic, and a special appendix that shows how to use MacLogic as a teaching aid. There are graded exercises at the end of each chapter--more than 900 in all--with selected answers at the end of the book. Unlike competing texts, Modern Logic (...) gives equal weight to semantics and proof theory and explains their relationship, and develops in detail techniques for symbolizing natural language in first-order logic. After a general introduction featuring the notion of logical form, the book offers sections on classical sentential logic, monadic predicate logic, and full first-order logic with identity. A concluding section deals with extensions of and alternatives to classical logic, including modal logic, intuitionistic logic, and fuzzy logic. For students of philosophy, mathematics, computer science, or linguistics, Modern Logic provides a thorough understanding of basic concepts and a sound basis for more advanced work. (shrink)

A verb is transitive iff it usually occurs with a direct object, and in such occurrences it is said to occur transitively . Thus ‘ate’ occurs transitively in ‘I ate the meat and left the vegetables’, but not in ‘I ate then left’ (perhaps it is not the same verb ‘left’ in these two examples, but it seems to be the same ‘ate’). A verb is intensional if the verb phrase (VP) it forms with its complement is anomalous in at (...) least one of three ways: (i) interchanging expressions in the complement referring to the same entity can change the truth-value of the sentence embedding the VP; (ii) the VP admits of a special “unspecific” reading if it contains a quantifier, or a certain type of quantifier; and (iii) the normal existential commitments of names and existential quantifiers in the complement are suspended even when the embedding sentence is negation-free. (shrink)

This paper discusses some recent responses to Kripke’s modal objections to descriptivism about names. One response, due to Gluer-Pagin and Pagin, involves employing "actually" operators in a new way. Another, developed mainly by Chalmers, involves distinguishing the dimension of meaning modal operators affect from the dimension other operators, especially epistemic ones, affect. I argue that both these moves run into problems with "mixed" contexts involving factive verbs such as "know", "establish", "prove", etc. In mixed contexts there are both modal and (...) epistemic operators, and it seems that some contradictory examples, such as "possibly (Hesperus has a moon and someone establishes that Hesperus has no moon)", are classified as true according to these views. (shrink)

This paper is about the cluster of issues that orbit a well-known thesis of Quine’s, as it applies to attitude ascriptions.

This paper is about two puzzles, or two versions of a single puzzle, which deserve to be called paradoxes, and develops some apparatus in terms of which the apparently conflicting principles which generate the puzzles can be rendered consistent. However, the apparatus itself is somewhat controversial: the puzzles are modal ones, and the resolution to be advocated requires the adoption of a counterpart theoretic semantics of essentially the kind proposed by David Lewis, which in turn requires qualified rejection of certain (...) modal theses about identity which are valid in S5. (shrink)